You're running an almost identical setup to mine. I'm going to take a stab here and say fertilizer buildup...here's why:
1) Using RO water it's not going to be a salt/chlorine issue.
2) AN pH perfect nutes should be delivering food at the correct pH or at least close, so I'm doubtful that's the culprit.
3) My cube of SS#4 advanced has always been pH'ed perfectly at 6.3...every single container I've filled with that stuff has been spot-on.
4) It's not light or heat burn/stress because there would be other symptoms in the form of leaf curl and/or other issues.
I would wait a few days until the pots feel nice and light, then do a plain water feeding with about 2 gallons per pot, wait an hour, then come back with another 2 - 5 gallons per pot and try to flush any salts out of the soil. Don't pH adjust your water when you do this, if you have a good RO it should be close to 7 anyway, test the runoff on the second watering to see where your soil pH is at. I get those spots for 2 reasons...too many nutes in the medium OR pH is about 2 points too low. Based on your choice of medium/nutes, I'm thinking it's not a pH issue.
Good luck!