I have this issue with every grow.it is almost like clock work.I am positive it has to do with the soil i use.I dont have much of a selection here in the u.p. of michigan.The soil i get from my farm supply store is a good mix with lots of perlite and such.But i always have to add cal-mag at some point. i dont believe it is a ph issue since i test run off at the onset of the issue.
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