It would be helpful to see some pics of the whole plant taken with the lights off or the plants removed from under the lights so we can see the true color of the leaves. If it's only a couple of the very bottom leaves it's fairly common to have them start to die off at this age, especially if they are well shaded. But if it's spreading up the plant, then it could be a deficiency. I also wouldn't overlook your pH. If your soil pH is off you could also be experiencing nutrient lockout. Are you checking the pH of your soil or of your run off? If so, what is it reading.